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SEM image of Staphylococcus bacteria

In Memoria:

The staff of the Central Microscopy Research Facility send their condolences to the family of Kenneth Charles Moore, founder and longtime UI CMRF Director.  May he rest in peace.

 

Celebrating 44 Years of Advancing University of Iowa Research

At the University of Iowa's Central Microscopy Research Facilities, we provide a wide variety of microscopy techniques for materials and biomedical investigators, an experienced staff, and support for the beginner and experienced investigator. As one of the leading university microscopy facilities in the nation, our microscopy team is ready to support your research program.

 

-------------------- CMRF News --------------------

 

Important Notice: The Xenogen IVIS 200 system will be relocated to room 120 PBDB on June 1, 2018

The Xenogen IVIS 200 system will be relocated to room 120 PBDB on June 1, 2018.  It will be under the direction of the Small Animal Imaging Core (SAIC).  Please contact Susan Walsh (susan-walsh@uiowa.edu, 335-9347) to establish an account and have access granted to that area.

 The CMRF will be changing to the Infinity Scheduling and Billing software in the near future, stay tuned

On May 1st the CMRF will change over to the state-of-the-art Infinity Core Facility Management software scheduling and billing software.  This advanced reservation and billing suite will streamline the instrument reservation process and will improve the accuracy and speed of the CMRF's Business Office.  Infinity will replace our antiquated OCF instrument reservation software package.

As of May 1st all CMRF equipment reservations must be made through the Infinity system. You will soon be sent information on how to login to the new system.

New Hours for Microtomy Room Access

Due to health and safety concerns for our investigators, the CMRF has begun limiting access to room 93 EMRB. The sectioning equipment located in this room is accessible during normal University business hours, typically 8:00am to 5:00pm, Monday through Friday. Room 93 is not available on evenings and weekends. If you have any questions please contact the CMRF office at 5-8142.

The CMRF is in the process of replacing its antiquated OCF instrument reservation software with the state-of-the-art Idea Elan Core Facility Management software package. This advanced reservation and billing suite will streamline the instrument reservation process and will improve the accuracy and speed of the CMRF's Business Office.  Stay tuned for more information.

FRAP and FRET for Leica SP8 Confocal/STED

The CMRF recently upgraded the Leica SP8 Confocal/STED microscope with FRAP and FRET software. The new modules use a “Wizard” format to guide you through configuration and data collection. FRAP and FRET software guides can be found on the SP8 website.

 

New High-end Workstation installed for Imaris 3D and 4D Real-time Interactive Visualization and Analysis Software.

Imaris

 

The CMRF recently installed a custom-built workstation to run its copy of Bitplane’s Imaris 3D and 4D Real-time Interactive Visualization and Analysis Software. Specifications of this high-end workstation include:

  • 128GB DDR4 RAM
  • 8-core Intel i7 Skylake CPU
  • 8GB DDR5 video display card with over 2,000 CUDA processing cores
  • All solid state hard drives

 

With just a few steps, Imaris delivers quantitative volumetric and motion-analysis results. Custom Imaris modules are available for neuroscience, (e.g. dendrite and spine analysis,) and co-localization studies. Other available features include:

  • Imaris Measurement Pro: Shape, size and intensity-based quantification.
  • Imaris Track: Imaging, tracking and motion analysis of live cells and moving objects in 2D and 3D.
  • Imaris Filament Tracer: Automatic detection of neurons (dendritic trees, axons and spines,) microtubules, and other filament-like structures in 2D, 3D and 4D.
  • Imaris Coloc: Quantify and document co-distribution of multiple stained biological components.
  • Imaris Cell: Quantitatively examine micro relationships that exist within and between cells.
  • Imaris Vantage: Compare and contrast experimental groups by visualizing image data in five dimensions as uni- or multi-variate scatterplots.

 

New High-Resolution Iridium Sputter Coater Available!

The CMRF has purchased a Quorum Technologies 150T ES Iridium sputter coater to support high-resolution SEM imaging. It is capable of producing coatings that are much thinner than standard Au/Pd sputter coating, which can result in higher-resolution images. The QT 150T ES is the ideal coating system for routine imaging above 50,000x. Contact CMRF staff if you are interested in using this instrument.

Office of Research and Economic Development article on the 2016 Art in Science Contest

 

CMRF Staff are available  Monday through Friday 8am-5pm and will be happy to assist you! Call 335-8142 or email Randy Nessler for more information.